Tuberous sclerosis or tuberous sclerosis complex (TSC) is a rare multi-system genetic disease that causes benign tumors to grow in the brain and on other vital organs such as the kidneys, heart, eyes, lungs, and skin. A combination of symptoms may include seizures, intellectual disability, developmental delay, behavioral problems, skin abnormaliti...
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http://en.wikipedia.org/wiki/Tuberous_sclerosis
(from the article `nervous system disease`) Tuberous sclerosis is characterized by epileptic seizures, a facial rash resembling acne, and benign tumours of the lining membrane of the ventricles ...
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http://www.britannica.com/eb/a-z/t/89
A genetic disorder in which benign (not cancer) tumors form in the kidneys, brain, eyes, heart, lungs, and skin. This disease can cause seizures, mental disabilities, and different types of skin lesions.
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http://www.cancer.gov/dictionary?expand=T
CaF directory of specific conditions and rare syndromes. Tuberous (swellings or enlargements) sclerosis (the hardening of an organ or tissue) is a complex heterogeneous genetic disorder which may affect many of the body systems. Typical manifestations occur in the brain, skin, eye, kidney, bones, lungs and intestine.
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http://www.encyclo.co.uk/local/20898
<radiology> (Bourneville disease) autosomal dominant phakomatosis classic triad: seizures, retardation, adenoma sebaceum, calcified subependymal hamartomas, uncalcified tubers in cerebral cortex, enhancing lesion most likely to be malignant transformation to giant cell astrocytoma associated with: skin lesions, angiomyolipoma, increased risk ...
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http://www.encyclo.co.uk/local/20973
an autosomal dominant disease with variable manifestations, primarily neurologic and dermatologic; it is usually evident in childhood, although mild cases may not appear until later. The primary characteristics are hamartomas of the brain (tubers) that can cause seizures and mental retardation; and skin lesions such as fibromas...
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http://www.encyclo.co.uk/local/21001
Autosomal dominant disorder caused by mutation in tumour suppressor genes TSC1 or TSC2. Disease characterized by range of features including seizures, mental retardation, renal dysfunction and dermatological abnormalities. TSC1 encodes hamartin, TSC2 encodes tuberin which has rap- and rab-GAPactivity.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Definitions: 1. phacomatosis characterized by the formation of multisystemic hamartomas producing seizures, mental retardation, and angiofibromas of the face; the cerebral and retinal lesions are glial nodules; other skin lesions are hypopigmented macules, shagreen patches, and periungual fibromas; autosomal dominant inheritance with var...
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http://www.medilexicon.com/medicaldictionary.php?t=80257
Tuberous sclerosis: A genetic disorder characterized by abnormalities of the skin, brain, kidney, and heart. The skin abnormalities are present in all cases and may include tiny benign tumors (angiofibroma) on the face and depigmented areas anywhere on the body. The brain abnormalities are mainly benign cortical tumors (tubers) which cause seizures...
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http://www.medterms.com/script/main/art.asp?articlekey=11454
Rare genetic disease that causes benign tumors to grow on vital organs. It commonly affects the central nervous system. More common in people with autism.
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https://www.encyclo.co.uk/local/20836
a genetic disorder of the skin and nervous system characterised by epilepsy, mental retardation, and a skin condition resembling acne
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https://www.encyclo.co.uk/local/20875
No exact match found.
